All Photos(2)



Anti-RAF1 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

Raf-1, c-Raf, NS5, CRAF

Quality Level

biological source




antibody form

purified immunoglobulin

antibody product type

primary antibodies




buffered aqueous solution

mol wt

antigen ~73.1 kDa

species reactivity



indirect immunofluorescence: suitable
western blot: 1 μg/mL

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.


Gene Information

human ... RAF1(5894)

General description

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. (provided by RefSeq)


RAF1 (NP_002871.1, 1 a.a. ~ 648 a.a) full-length human protein.


Physical form

Solution in phosphate buffered saline, pH 7.4


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

13 - Non Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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