Anti-APBA1/MINT1 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Anti-Amyloid-β, Anti-D9S411E, Anti-MINT1
MDL number:

Quality Level

biological source


antibody form

affinity isolated antibody

antibody product type

primary antibodies




buffered aqueous solution

species reactivity

rat, mouse, human


indirect ELISA: suitable
western blot: suitable



UniProt accession no.

shipped in

dry ice

storage temp.


Gene Information

human ... APBA1(320)

General description

APBA1 (Amyloid β (A4) precursor protein binding, family A, member 1) is a neuronal adaptor protein belonging to the X11 family. It consists of a centrally located phosphotyrosine binding domain which inhibits the production of Aβ peptide, two C-terminal postsynaptic density-95, large discs, zona occludens 1 (PDZ) domains.


Peptide with sequence C-EASHPSQDGKRQYK from the internal region of the protein sequence according to NP_001154.2.


Anti-APBA1/MINT1 antibody produced in goat is suitable for indirect ELISA and western blot analysis.

Biochem/physiol Actions

APBA1 (Amyloid β (A4) precursor protein binding, family A, member 1) stabilizes amyloid precursor protein (APP) by directly interacting with it. It also restricts production as well as accumulation of proteolytic APP fragment in the brain of Alzheimer′s disease patients. It also suppresses glycogen synthase kinase-3β promoter activity by coupling with a silencer binding protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.


Exclamation mark

Signal Word


Hazard Statements

Precautionary Statements


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Ju-Hyun Lee et al.
The Journal of biological chemistry, 278(47), 47025-47029 (2003-09-13)
Increased production and deposition of the 40-42-amino acid beta-amyloid peptide (Abeta) is believed to be central to the pathogenesis of Alzheimer's disease. Abeta is derived from the amyloid precursor protein (APP), but the mechanisms that regulate APP processing to produce...
Kwok-Fai Lau et al.
Neuroreport, 21(11), 761-766 (2010-06-10)
X11alpha is a neuronal adaptor protein that interacts with the amyloid precursor protein (APP) through a centrally located phosphotyrosine binding domain to inhibit the production of Abeta peptide that is deposited in Alzheimer's disease brains. X11alpha also contains two C-terminal...

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