SAB2500116

Sigma-Aldrich

Anti-ARPC4 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):
Anti-ARC20, Anti-MGC13544
NACRES:
NA.41
Pricing and availability is not currently available.

biological source

goat

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, mouse

application(s)

indirect ELISA: suitable
western blot: suitable

conjugate

unconjugated

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... ARPC4(10093)

General description

The gene ARPC4 (actin-related protein 2/3 complex subunit 4) is mapped to human chromosome 3p25. It is a component of the actin related protein 2/3 (Arp2/3) complex.

Immunogen

Peptide with sequence C-ERHNKPEVEVR from the internal region of the protein sequence according to NP_005709.1.

Biochem/physiol Actions

The actin related protein 2/3 (Arp2/3) protein complex serves as an actin nucleator and it helps in actin filament branching. The complex is associated with phagocytosis, vesicular trafficking, lamellipodia extension and cytokinesis. ARPC4 is required to connect the complex with actin filament.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
The diverse family of Arp2/3 complexes
Pizarro-Cerda, et al.
Trends in Cell Biology, 27(2), 93-100 (2017)
Silencing of the ARP2/3 complex disturbs pancreatic cancer cell migration
Rauhala HE, et al.
Anticancer Research, 33(1), 45-52 (2013)
3p- syndrome defines a hearing loss locus in 3p25.3
McCullough BJ, et al.
Hearing Research, 224(1-2), 51-60 (2007)

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