SAB2500895

Sigma-Aldrich

Anti-RPE65 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):
Anti-Retinal pigment epithelium-specific protein 65 kDa, Anti-LCA2, Anti-RP20, Anti-Rd12, Anti-SRPE65
NACRES:
NA.41

Quality Level

biological source

goat

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

canine, human

application(s)

indirect ELISA: suitable
western blot: suitable

conjugate

unconjugated

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... RPE65(6121)

Immunogen

Peptide with sequence C-EVKKNARKAPQPE from the internal region of the protein sequence according to NP_000320.1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Ye Liu et al.
Molecular therapy. Nucleic acids, 17, 113-125 (2019-06-30)
The receptor-associated prorenin system refers to the pathogenic mechanism whereby prorenin binding to (pro)renin receptor [(P)RR] dually activates the tissue renin-angiotensin system (RAS) and RAS-independent signaling, and its activation contributes to the molecular pathogenesis of various ocular diseases. We recently...
Giorgia Fanelli et al.
Scientific reports, 7(1), 14625-14625 (2017-11-09)
Age-related macular degeneration (AMD) is a major cause of blindness and is associated with complement dysregulation. The disease is a potential target for stem cell therapy but success is likely to be limited by the inflammatory response. We investigated the...
Rajalekshmy Shyam et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(41), 10882-10887 (2017-09-07)
Carotenoids are plant-derived pigment molecules that vertebrates cannot synthesize de novo that protect the fovea of the primate retina from oxidative stress and light damage.
Anni Sorkio et al.
Journal of tissue engineering and regenerative medicine, 11(11), 3134-3144 (2017-01-05)
Human embryonic stem cell-derived retinal pigment epithelial (hESC-RPE) cell therapies show tremendous potential for the treatment of retinal degenerative diseases. A tissue engineering approach, where cells are delivered to the subretinal space on a biodegradable carrier as a sheet, shows...
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