SAB2501166

Anti-EBF1 antibody produced in goat

Name: Anti-EBF1 antibody produced in goat
Brand: SIGMA
Price: 628 USD

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-COE1, Anti-EBF, Anti-FLJ39389, Anti-FLJ41763, early B-cell factor 1

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100 μG

$628.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

About This Item

MDL number:

MFCD03791484

UNSPSC Code:

12352203

NACRES:

NA.41

Key Documents

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biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, mouse, rat

technique(s)

immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: suitable

UniProt accession no.

Q9UH73

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EBF1(1879)

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This Item	SAB1403753	HPA061169	E8156
Sigma-Aldrich SAB2501166 Anti-EBF1 antibody produced in goat	Sigma-Aldrich SAB1403753 Monoclonal Anti-EBF antibody produced in mouse	Sigma-Aldrich HPA061169 Anti-EBF1 antibody produced in rabbit	Sigma-Aldrich E8156 Anti-eRF1 antibody produced in rabbit
biological source goat	biological source mouse	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form affinity isolated antibody
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 200
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
shipped in dry ice	shipped in dry ice	shipped in wet ice	shipped in dry ice

Immunogen

Peptide with sequence CHNQLPALANTSV, from the internal region of the protein sequence according to NP_076870.1.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper)
Immunoprecipitation (1 paper)

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

7809C2G2

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Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks.

Jan-Philipp Mallm et al.

Molecular systems biology, 15(5), e8339-e8339 (2019-05-24)

In chronic lymphocytic leukemia (CLL), a diverse set of genetic mutations is embedded in a deregulated epigenetic landscape that drives cancerogenesis. To elucidate the role of aberrant chromatin features, we mapped DNA methylation, seven histone modifications, nucleosome positions, chromatin accessibility

MEF2C and EBF1 Co-regulate B Cell-Specific Transcription.

Nikki R Kong et al.

PLoS genetics, 12(2), e1005845-e1005845 (2016-02-24)

Hematopoietic stem cells are capable of self-renewal or differentiation along three main lineages: myeloid, erythroid, and lymphoid. One of the earliest lineage decisions for blood progenitor cells is whether to adopt the lymphoid or myeloid fate. Previous work had shown

Long noncoding RNA IL6-AS1 is highly expressed in chronic obstructive pulmonary disease and is associated with interleukin 6 by targeting miR-149-5p and early B-cell factor 1.

Erkang Yi et al.

Clinical and translational medicine, 11(7), e479-e479 (2021-07-30)

Chronic obstructive pulmonary disease is a complex condition with multiple etiologies, including inflammation. We identified a novel long noncoding RNA (lncRNA), interleukin 6 antisense RNA 1 (IL6-AS1), which is upregulated in this disease and is associated with airway inflammation. We

B Lymphocyte Specification Is Preceded by Extensive Epigenetic Priming in Multipotent Progenitors.

Tobias Strid et al.

Journal of immunology (Baltimore, Md. : 1950), 206(11), 2700-2713 (2021-05-23)

B lymphocyte development is dependent on the interplay between the chromatin landscape and lineage-specific transcription factors. It has been suggested that B lineage commitment is associated with major changes in the nuclear chromatin environment, proposing a critical role for lineage-specific

Ebf1 and c-Myb repress rag transcription downstream of Stat5 during early B cell development.

Greg A Timblin et al.

Journal of immunology (Baltimore, Md. : 1950), 191(9), 4676-4687 (2013-09-27)

The temporal control of RAG (Rag) expression in developing lymphocytes prevents DNA breaks during periods of proliferation that could threaten genomic integrity. In developing B cells, the IL-7R and precursor B cell Ag receptor (pre-BCR) synergize to induce proliferation and

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