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MilliporeSigma

SAB2702233

Monoclonal Anti-Dengue virus Envelope protein antibody produced in mouse

clone GT643, affinity isolated antibody

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100 μL

$519.00

$519.00


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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
GT643, monoclonal
Application:
FACS, IF, WB
Species reactivity:
Dengue virus
Citations:
4
Technique(s):
flow cytometry: suitable, immunofluorescence: 1:100-1:2,000, western blot: 1:500-1:3,000

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biological source

mouse

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

GT643, monoclonal

form

buffered aqueous solution

mol wt

51-60kDa

species reactivity

Dengue virus

concentration

1mg/mL

technique(s)

flow cytometry: suitable, immunofluorescence: 1:100-1:2,000, western blot: 1:500-1:3,000

isotype

IgG2b

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

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1 of 4

This Item
MAB8701MAB8702SAB2702232
biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

clone

GT643, monoclonal

clone

15F3-1, monoclonal

clone

3H5-1, monoclonal

clone

GT214, monoclonal

conjugate

unconjugated

conjugate

-

conjugate

-

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

species reactivity

Dengue virus

species reactivity

human

species reactivity

human

species reactivity

Dengue virus

isotype

IgG2b

isotype

IgG1

isotype

IgG1

isotype

IgG2a

Other Notes

Purification: Affinity purified by Protein G

Physical form

Phosphate-buffered saline, no preservative added.

Application

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:2000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Dengue virus is an arthropod borne flavivirus. Dengue virus (DENV) is a human pathogen, known to cause one of the major illness, dengue fever (DF) in humans. DENV belongs to the Flaviviridae family. The virus attaches and enters the host cell with the help of a major envelope protein glycoprotein, E. The dengue envelope protein sequence consists of two putative glycosaminoglycan-binding motifs at the carboxy terminus.

Immunogen

Recombinant protein encompassing a sequence within the center region of Dengue virus Envelope protein.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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A ligand-binding pocket in the dengue virus envelope glycoprotein.
Modis Y, et al.
Proceedings of the National Academy of Sciences of the USA, 100(12), 6986-6991 (2003)
Type-and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes.
Sukupolvi-Petty S, et al.
Journal of Virology, 81(23), 12816-12826 (2007)
Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate.
Chen Y, et al.
Nature Medicine, 3(8), 866-866 (1997)
Ankit Kumar et al.
Asian journal of transfusion science, 16(1), 67-72 (2022-10-07)
The study objective was evaluation of amotosalen and ultraviolet A (UVA) illumination-based inactivation of dengue virus (DENV) in blood platelets. Whole blood was collected from healthy donors and platelet concentrates were prepared at a tertiary care hospital in Gurugram, India.

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