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Anti-CTRP6 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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biological source


Quality Level



antibody form

affinity isolated antibody

antibody product type

primary antibodies




buffered aqueous solution

species reactivity

human, mouse


immunocytochemistry: suitable
indirect ELISA: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.


target post-translational modification


Gene Information

General description

C1q and TNF (Tumour necrosis factor) related protein 6 (CTRP6/C1QTNF6) is a glycoprotein which belongs to family of proteins containing TNF alpha-like globular domain. CTRP6 is a single peptide with a short variable region, a collagen like region, and a C-terminal globular domain. CTRP6 is expressed in human synoviocytes. In human chromosome, the gene is localized on 22q12.3.


CTRP6 antibody was raised against a 15 amino acid peptide from near the carboxy-terminus of human CTRP6.

Biochem/physiol Actions

C1q and TNF (Tumour necrosis factor) related protein 6 (CTRP6) plays a major role in fatty acid metabolism. CTRP6 phosphorylates AMCK (5′-AMP (adenosine monophosphate)-activated protein kinase) and ACC (acetyl coenzyme A carboxylase) and activates AMCK-ACC pathway. The expression level of CTRP6 is increased in rheumatoid arthritis. CTRP6 inhibits alternative complement pathway and helps in maintaining pregnancy. CTRP6 mediates the ectopic lipogenesis in myoblasts through AdipoR1/Erk/PPARγ (Adiponectin receptor 1/Extracellular signal-regulated kinases/Peroxisome proliferator-activated receptor gamma) signalling pathway. CTRP6 is overexpressed in hepatocellular carcinoma and stimulates angiogenesis by Akt (serine/threonine-protein kinase) pathway. CTRP6 confers susceptibility to type I diabetes. CTRP6 maybe a key regulator connecting obesity with tissue inflammation and insulin resistance.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.


The action of this antibody can be blocked using blocking peptide SBP3500196.

Physical form

Supplied in PBS with 0.02% sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids




Not applicable


Not applicable

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