SAB3500274

Anti-Amyloid Precursor Protein (APP) Antibody

Name: Anti-Amyloid Precursor Protein (APP) Antibody
Brand: SIGMA
Price: 584 USD

rabbit polyclonal

Synonym(s):

Anti-APP(AbNT)

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100 μG

$584.00

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A recombinant, preservative-free antibody is available for your target. Try ZRB1151

About This Item

MDL number:

MFCD03096620

UNSPSC Code:

12352203

NACRES:

NA.41

Key Documents

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Product Name

Anti-APP antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 83 kDa

species reactivity

human, mouse, rat

technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

NCBI accession no.

CAA30050

UniProt accession no.

P05067

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... APP(351)

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Show Differences

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This Item	SAB5200113	HPA001462	SAB4300464
Sigma-Aldrich SAB3500274 Anti-APP antibody produced in rabbit	Sigma-Aldrich SAB5200113 Anti-APP antibody produced in rabbit	Sigma-Aldrich HPA001462 Anti-APP antibody produced in rabbit	Sigma-Aldrich SAB4300464 Anti-APP (Ab-668) antibody produced in rabbit
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
shipped in dry ice	shipped in wet ice	shipped in wet ice	shipped in wet ice
UniProt accession no. P05067	UniProt accession no. P05067	UniProt accession no. P05067	UniProt accession no. P05067

Immunogen

APP antibody was raised against a peptide corresponding to amino acids of human amyloid A4 protein precursor (APP) corresponding to the amino terminus of the 4K Ab peptide generated by b- and g-secretases The peptide sequences are identical to those of ra

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500274.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Description

Pricing

SBP3500274

APP / AbNT Blocking Peptide for SAB3500274

ZRB1516

Anti-APP Antibody, clone 1F22 ZooMAb^® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

21330604

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Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease.

Carla M Yuede et al.

Journal of neurochemistry, 156(5), 658-673 (2020-12-06)

Amyloid-β (Aβ) peptide aggregation into soluble oligomers and insoluble plaques is a precipitating event in the pathogenesis of Alzheimer's disease (AD). Given that synaptic activity can regulate Aβ generation, we postulated that 5HT2A -Rs may regulate Aβ as well. We

Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver.

Gayane Hrachia Buniatian et al.

Cells, 9(2) (2020-02-25)

The function and regulation of amyloid-beta (Aβ) in healthy and diseased liver remains unexplored. Because Aβ reduces the integrity of the blood-brain barrier we have examined its potential role in regulating the sinusoidal permeability of normal and cirrhotic liver. Aβ

Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer's disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis.

Hei-Jen Huang et al.

BMC complementary medicine and therapies, 21(1), 259-259 (2021-10-11)

According to recent evidence, psychobiotics exert beneficial effects on central nervous system-related diseases, such as mental disorders. Lactobacillus plantarum PS128 (PS128), a novel psychobiotic strain, improves motor function, depression, and anxiety behaviors. However, the psychobiotic effects and mechanisms of PS128

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