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SAB3500350

Sigma-Aldrich

Anti-β-Actin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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Synonym(s):
Anti-β-actin
MDL number:
NACRES:
NA.41

biological source

chicken

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, human, mouse

technique(s)

indirect ELISA: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ACTB(60)

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This Item
A1978A2228SAB4502632
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

chicken

biological source

mouse

biological source

mouse

biological source

rabbit

species reactivity

rat, human, mouse

species reactivity

sheep, carp, feline, chicken, rat, mouse, Hirudo medicinalis, rabbit, canine, pig, human, bovine, guinea pig

species reactivity

rabbit, sheep, cat, guinea pig, bovine, mouse, chicken, wide range, Hirudo medicinalis, canine, Drosophila, carp, pig, rat, human

species reactivity

rat, mouse, human

UniProt accession no.

P60709

UniProt accession no.

P60709

UniProt accession no.

P60709

UniProt accession no.

P63261

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

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General description

The amino-terminal of actin may function as an antigen. The protein is expressed in the cytoplasm. There are about six isoforms of actin identified.

Immunogen

β-actin antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of human β-actin.

Application

Anti-β-Actin antibody produced in chicken has been used for Western Blotting.

Biochem/physiol Actions

Actin is a cytoskeletal protein that regulates cell motility, secretion, cytoplasmic streaming, phagocytosis and cytokinesis. Mutations in the gene encoding this protein have been associated with Baraitser-Winter cerebrofrontofacial syndrome.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Regulation of the macrophage oxytocin receptor in response to inflammation
Angela Szeto
The American Journal of Physiology (2017)
Y Huang et al.
Genes and immunity, 13(4), 311-320 (2012-01-27)
Depending on the environment, dendritic cells (DCs) may become active or tolerogenic, but little is known about whether heritable epigenetic modifications are involved in these processes. Here, we have found that epigenetic histone modifications can regulate the differentiation of human
Rachel E Bennett et al.
Proceedings of the National Academy of Sciences of the United States of America, 115(6), E1289-E1298 (2018-01-24)
Mixed pathology, with both Alzheimer's disease and vascular abnormalities, is the most common cause of clinical dementia in the elderly. While usually thought to be concurrent diseases, the fact that changes in cerebral blood flow are a prominent early and
Angela Szeto et al.
Lipids in health and disease, 19(1), 188-188 (2020-08-21)
Obesity and adipose tissue expansion is characterized by a chronic state of systemic inflammation that contributes to disease. The neuropeptide, oxytocin, working through its receptor has been shown to attenuate inflammation in sepsis, wound healing, and cardiovascular disease. The current
Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin
European Journal of Biochemistry, 90 (1978)

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