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SAB3501247

Sigma-Aldrich

Anti-Swine H1N1 Hemagglutinin antibody produced in rabbit

affinity isolated antibody

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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

species reactivity

Influenza A virus subtype H1N1 (swine)

concentration

1 mg/mL

technique(s)

ELISA: suitable

isotype

IgG

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

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This Item
SAB3501249SAB3500061SAB3500059
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

form

liquid

form

liquid

form

buffered aqueous solution

form

buffered aqueous solution

species reactivity

Influenza A virus subtype H1N1 (swine)

species reactivity

Influenza A virus subtype H1N1 (swine)

species reactivity

viral

species reactivity

viral

General description

Swine H1N1 Hemagglutinin Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic. Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. The distinct antigenic properties of the new swine virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups.

Immunogen

Hemagglutinin antibody was raised against a synthetic peptide from the novel swine influenza Hemagglutinin protein.The peptide sequence is unique from the peptide sequence for product SAB3501249 and SAB3501245. This antibody is a cognate pair with product SAB3501246. The immunogen is located within amino acids 180 - 230 of Swine H1N1 Hemagglutinin.

Application

Hemagglutinin antibody can be used for the detection of the Hemagglutinin protein from the H1N1 strain of swine influenza A in ELISA. It will detect 2 ng of free peptide at 1 μg/mL.

Physical form

Supplied in PBS containing 0.02% sodium azide.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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