We do not know if this SAB4200678 antibody reacts with monkey. This product has only been tested against pig, rat, human, deer, and bovine in which it reacts to.
SAB4200678
Anti-Collagen Type I antibody, Mouse monoclonal
clone COL-1, purified from hybridoma cell culture
Synonym(s):
Monoclonal Anti-Collagen Type I antibody produced in mouse, OI4, alpha 1, alpha 2, collagen, type I
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About This Item
NACRES:
NA.41
UNSPSC Code:
51111800
Clone:
COL-1, monoclonal
Species reactivity:
pig, rat, human, deer, bovine
Application:
DB, ELISA, IHC
Technique(s):
ELISA: suitable, dot blot: suitable, immunoblotting: 1-2 μg/mL using recombinant human collagen, expressed in Nicotiana tabacum, immunohistochemistry: 3.5-7 μg/mL using frozen sections of human tonsil, human tongue or pig tongue
Citations:
20
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biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
COL-1, monoclonal
form
buffered aqueous solution
species reactivity
pig, rat, human, deer, bovine
concentration
~1 mg/mL
technique(s)
ELISA: suitable, dot blot: suitable, immunoblotting: 1-2 μg/mL using recombinant human collagen, expressed in Nicotiana tabacum, immunohistochemistry: 3.5-7 μg/mL using frozen sections of human tonsil, human tongue or pig tongue
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... COL1A1(1277)
1 of 4
This Item | SAB4200749 | SAB4500362 | ABT256 |
|---|---|---|---|
| clone COL-1, monoclonal | clone FH-7A, monoclonal | clone polyclonal | clone polyclonal |
| antibody form purified immunoglobulin | antibody form purified from hybridoma cell culture | antibody form affinity isolated antibody | antibody form affinity isolated antibody |
| Gene Information human ... COL1A1(1277) | Gene Information human ... COL3A1(1281) | Gene Information human ... COL1A2(1278) | Gene Information human ... COL1A1(1277) |
| species reactivity pig, rat, human, deer, bovine | species reactivity rat, human | species reactivity mouse, human, rat | species reactivity mouse, human, sheep |
| biological source mouse | biological source mouse | biological source rabbit | biological source rabbit |
| Quality Level 300 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
Physical form
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
Application
Monoclonal Anti-Collagen Type I antibody produced in mouse has been used in immunohistochemical analysis and in vitro invasion assays.
Biochem/physiol Actions
Collagen, type I (COL1A1) is an important component of the connective tissue matrix. It plays an important role in the growth and maintenance of organ and tissue integrity. This protein also participates in the process of tissue repair. COL1A1 is implicated in fibrosis.
Collagens are involved in structural roles. Additionally, they associate with various receptors and control cell proliferation, migration as well as differentiation.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Collagen type Iα1 (COL1A1) is encoded by the gene that is located on human chromosome 17q21.33. It is the most abundant extracellular matrix (ECM) protein in humans. Type 1 collagen is the major structural protein of bone, tendon, skin and cornea. The encoded protein is a heterotrimer consisting of two α1-chains and one α2-chain.
Collagens are present in the extracellular matrix and contains a chains which can differ in length.
Immunogen
bovine skin collagen type I
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Overexpression of CXCR4 promotes invasion and migration of non?small cell lung cancer via EGFR and MMP?9.
Zuo J, et al.
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International journal of molecular sciences, 25(14) (2024-07-27)
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Paeoniflorin prevents postoperative peritoneal adhesion formation in an experimental rat model.
Gao Q, et al.
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Deregulation of the platelet-derived growth factor β-chain gene via fusion with collagen gene COL1A1 in dermatof ibrosarcoma protuberans and giant-cell fibroblastoma.
Simon M-P, et al.
Nature Genetics, 15(10), 95-95 (1997)
Uwe Schwartz et al.
The EMBO journal, 42(12), e111272-e111272 (2023-05-05)
Patients with chronic obstructive pulmonary disease (COPD) are still waiting for curative treatments. Considering its environmental cause, we hypothesized that COPD will be associated with altered epigenetic signaling in lung cells. We generated genome-wide DNA methylation maps at single CpG
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Instruction
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Does this monoclonal antibody (SAB4200678) cross react to cyno monkey?
1 answer-
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i wonder to know if this antibody suitable for ICC assay on MC3T3E1 cell?
1 answer-
For SAB4200678, we have not studied this antibody on ICC assays. We have studied the following applications: ELISA: suitable
Dot blot: suitable. Immunoblotting: 1-2 μg/mL using recombinant human collagen expressed in Nicotiana tabacum. Immunohistochemistry: 3.5-7 μg/mL using frozen sections of human tonsil, human tongue, or pig tongue.Helpful?
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