SAB4300145

Anti-phospho-MAP3K5 (pSer⁸³) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-ASK1 antibody produced in rabbit, Anti-MAPKKK5 antibody produced in rabbit, Anti-MEKK5 antibody produced in rabbit, Anti-mitogen-activated protein kinase kinase kinase 5 antibody produced in rabbit
• MDL number: MFCD02262559
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~155 kDa
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (G-S-SP-V-G)
• NCBI accession no.: NP_005914.1
• UniProt accession no.: Q99683
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer83)
• Gene Information: human ... MAP3K5(4217)

Description

Immunogen

Peptide sequence around phosphorylation site of serine 83 (G-S-S(p)-V-G), according to the protein MAP3K5.

Features and Benefits

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Target description

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable