SAB4300155

Anti-phospho-HDAC4 (pSer⁶³²) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-HA6116 antibody produced in rabbit, Anti-HD4 antibody produced in rabbit, Anti-HDAC-A antibody produced in rabbit, Anti-HDACA antibody produced in rabbit, Anti-histone deacetylase 4 antibody produced in rabbit
• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: polyclonal
• Application: western blot
• Species reactivity: mouse, rat, human
• Citations: 1
• Technique(s): western blot: 1:500-1:1000
• Uniprot accession no.: P56524

Properties

• Product Name: Anti-phospho-HDAC4 (pSer⁶³²) antibody produced in rabbit, affinity isolated antibody
• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~140 kDa
• species reactivity: mouse, rat, human
• concentration: 1 mg/mL
• technique(s): western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (A-Q-SP-S-P)
• NCBI accession no.: NP_006028.2
• UniProt accession no.: P56524
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer632)
• Quality Level: 100
• Gene Information: human ... HDAC4(9759)

Description

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Immunogen

Peptide sequence around phosphorylation site of serine 632 (A-Q-S(p)-S-P), according to the protein HDAC4.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable