SAB4300194

Sigma-Aldrich

Anti-phospho-MAPK3 (pThr202) antibody produced in rabbit

affinity isolated antibody

Synonym(s):
Anti-ERK1 antibody produced in rabbit, Anti-mitogen-activated protein kinase 3 antibody produced in rabbit, Anti-HS44KDAP antibody produced in rabbit, Anti-HUMKER1A antibody produced in rabbit, Anti-MGC20180 antibody produced in rabbit
MDL number:
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~42 kDa
~44 kDa

species reactivity

mouse, human, rat

concentration

1 mg/mL

application(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(F-L-TP-E-Y)

conjugate

unconjugated

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... MAPK3(5595)

Immunogen

Peptide sequence around phosphorylation site of threonine 202 (F-L-T(p)-E-Y), according to the protein MAPK3.

Features and Benefits

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Target description

Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

storage_class_code

12 - Non Combustible Liquids

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Jia-Yun Li et al.
Cellular & molecular immunology, 11(5), 477-494 (2014-04-29)
Brucella abortus is a zoonotic Gram-negative pathogen that causes brucelosis in ruminants and humans. Toll-like receptors (TLRs) recognize Brucella abortus and initiate antigen-presenting cell activities that affect both innate and adaptive immunity. In this study, we focused on recombinant Brucella...
Miwa Tanaka et al.
The Journal of clinical investigation, 124(7), 3061-3074 (2014-06-10)
Ewing's sarcoma is a highly malignant bone tumor found in children and adolescents, and the origin of this malignancy is not well understood. Here, we introduced a Ewing's sarcoma-associated genetic fusion of the genes encoding the RNA-binding protein EWS and...
Fumihito Noguchi et al.
PloS one, 9(8), e102271-e102271 (2014-08-15)
MED1 (Mediator complex subunit 1) is a co-activator of various transcription factors that function in multiple transcriptional pathways. We have already established keratinocyte-specific MED1 null mice (Med1(epi-/-)) that develop epidermal hyperplasia. Herein, to investigate the function(s) of MED1 in skin...
Stanislav Avdieiev et al.
Bioorganic & medicinal chemistry, 22(15), 3815-3823 (2014-07-12)
Glioblastoma (GB), the most aggressive brain tumour, and mantle cell lymphoma (MCL), a rare but very aggressive type of lymphoma, are highly resistant to chemotherapy. GB and MCL chemotherapy gives very modest results, the vast majority of patients experience recurrent...
Mattia Capulli et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 29(8), 1833-1846 (2014-03-13)
Chondroadherin (CHAD) is a leucine-rich protein promoting cell attachment through binding to integrin α2 β1 and syndecans. We observed that CHAD mRNA and protein were lower in bone biopsies of 50-year-old to 65-year-old osteoporotic women and in bone samples of...

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