SAB4300617
Anti-phospho-Cdc25b (pSer149) antibody produced in rabbit
affinity isolated antibody
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Synonym(s):
Anti-AI604853 antibody produced in rabbit, Anti-Cdc25b antibody produced in rabbit, Anti-cell division cycle 25 homolog B (S. pombe) antibody produced in rabbit
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
~62 kDa
species reactivity
mouse
concentration
1 mg/mL
technique(s)
western blot: 1:500-1:1000
isotype
IgG
immunogen sequence
(F-R-SP-L-P)
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer149)
Gene Information
mouse ... Cdc25b(12531)
Immunogen
Peptide sequence around phosphorylation site of Serine 149 (F-R-S(p)-L-P).according to the protein Cdc25b.
Features and Benefits
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Target description
Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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