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SAB4300676

Sigma-Aldrich

Anti-Vimentin antibody produced in rabbit

affinity isolated antibody

Synonym(s):
Anti-FLJ36605, Anti-VIM
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~57 kDa

species reactivity

mouse, human, rat, monkey

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(G-Q-V-I-N)

NCBI accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... Vimentin(7431)

General description

Vimentin is a specific type III intermediate filament (IF) protein. It is abundantly expressed in mesenchymal cells. It is located on human chromosome 10p13.

The antibody detects endogenous level of total Vimentin protein.

Immunogen

Peptide sequence around aa. 452-456 (G-Q-V-I-N), according to the protein NP_003371.2

Biochem/physiol Actions

Vimentin helps to preserve the structure of cell and stability of tissue in mesenchymal cells. It is involved in tumorigenesis, EMT (epithelial mesenchymal transition) and the metastatic spread of cancer. It also controls infectious internalization of human papillomavirus 16 pseudovirions.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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