SAB4301144

Sigma-Aldrich

Anti-CEACAM8 antibody produced in rabbit

affinity isolated antibody

Synonym(s):
CD67, CD66b, NCA-95, CGM6
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

concentration

1.2 mg/mL

application(s)

immunohistochemistry: 1:50- 1:200

isotype

IgG

accession no.

NP_001807.2

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CEACAM8(1088)

Specificity

The antibody detects endogenous levels of total CEACAM8 protein.

Immunogen

Fusion protein corresponding to a region derived from internal residues of human carcinoembryonic antigen-related cell adhesion molecule 8

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

storage_class_code

12 - Non Combustible Liquids

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Jasper Callemeyn et al.
Journal of the American Society of Nephrology : JASN, 31(9), 2168-2183 (2020-07-10)
Circulating donor-specific anti-HLA antibodies (HLA-DSAs) are often absent in serum of kidney allograft recipients whose biopsy specimens demonstrate histology of antibody-mediated rejection (ABMR). It is unclear whether cases involving ABMR histology without detectable HLA-DSAs represent a distinct clinical and molecular...
Charitharth Vivek Lal et al.
JCI insight, 3(5) (2018-03-09)
Premature infants are at high risk for developing bronchopulmonary dysplasia (BPD), characterized by chronic inflammation and inhibition of lung development, which we have recently identified as being modulated by microRNAs (miRNAs) and alterations in the airway microbiome. Exosomes and exosomal...
Mieke Metzemaekers et al.
Journal of leukocyte biology, 107(6), 1167-1173 (2020-04-10)
CXCL8 is the principal human neutrophil-attracting chemokine and a major mediator of inflammation. The chemokine exerts its neutrophil-chemotactic and neutrophil-activating activities via interaction with glycosaminoglycans (GAGs) and activation of the G protein-coupled receptors (GPCRs) CXCR1 and CXCR2. Natural CXCL8 displays...
Krystle Kq Yu et al.
JCI insight, 6(6) (2021-02-24)
Comorbid medical illnesses, such as obesity and diabetes, are associated with more severe COVID-19, hospitalization, and death. However, the role of the immune system in mediating these clinical outcomes has not been determined. We used multiparameter flow cytometry and systems...
Michael Klichinsky et al.
Nature biotechnology, 38(8), 947-953 (2020-05-04)
Chimeric antigen receptor (CAR) T cell therapy has shown promise in hematologic malignancies, but its application to solid tumors has been challenging1-4. Given the unique effector functions of macrophages and their capacity to penetrate tumors5, we genetically engineered human macrophages...

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