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MilliporeSigma

SAB4301756

Anti-PF4

affinity isolated antibody

Synonym(s):

CXCL4, PF-4, SCYB4

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100 μL

$408.00

$408.00


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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human

technique(s)

immunohistochemistry: 1:20-1:100

accession no.

NP_002610

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PF4(5196)

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This Item
WH0005196M1SAB5701480MABS1255
Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

mouse

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

-

antibody form

purified immunoglobulin

UniProt accession no.

P02776

UniProt accession no.

P02776

UniProt accession no.

P02776

UniProt accession no.

P02776

technique(s)

immunohistochemistry: 1:20-1:100

technique(s)

immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

technique(s)

ELISA: suitable, flow cytometry: suitable, immunocytochemistry: suitable, western blot: suitable

species reactivity

human

species reactivity

human

species reactivity

mouse, human, rat

species reactivity

human

General description

Platelet factor-4 (PF-4) is a CXC chemokine that is expressed in megakaryocytes and stored in the alpha-granules of platelets. The gene encoding this protein is localized on human chromosome 4.

Immunogen

Synthetic peptide of human PF4

Biochem/physiol Actions

Platelet factor-4 (PF-4) is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. This protein associates with heparin and neutralizes it. It also neutralizes various negatively charged proteoglycans.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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CXCL4 Plasma Levels Are Not Associated with the Extent of Coronary Artery Disease or with Coronary Plaque Morphology.
Erbel C
PLoS ONE, 10(11), ee0141693-ee0141693 (2015)
Chemokines and Chemokine Receptors
Manel Juan
Wiley Interdisciplinary Reviews. RNA null
Transformation-associated cytokine 9E3/CEF4 is chemotactic for chicken peripheral blood mononuclear cells.
Barker KA
Journal of Virology, 67(6), 3528-3533 (1993)
CXCL4-platelet factor 4, heparin-induced thrombocytopenia and cancer.
Sandset PM
Thrombosis Research, 129, S97-100 (2012)

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