SAB4500675

Anti-MKP1 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): 3CH134, CL100, DUS1, Dual specificity protein phosphatase 1, Dual specificity protein phosphatase hVH1
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 39 kDa
• species reactivity: human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P28562
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... DUSP1(1843)

Description

General description

Anti-MKP1 Antibody detects endogenous levels of total MKP1 protein.

MKP1 (mitogen-activated protein kinase phosphatase 1)/DUSP1 (dual specificity phosphatase 1) is a dual specificity phosphatase. It is also called as CL100, 3CH134 and Erp. MKP1 is located in the nucleus and is expressed in several tissues. It is located on human chromosome 5q35.

Immunogen

The antiserum was produced against synthesized peptide derived from human MKP1.

Immunogen Range: 318-367

Biochem/physiol Actions

In mast cells, MKP1 (mitogen-activated protein kinase phosphatase 1) blocks the functions of extracellular signal-regulated kinase (Erk)‐1/2 by glucocorticoid. It controls axon branching promoted by BDNF (brain-derived neurotrophic factor).

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable