Anti-GFAP antibody produced in rabbit

affinity isolated antibody

Glial fibrillary acidic protein

biological source


Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies




buffered aqueous solution

mol wt

antigen 49 kDa

species reactivity



~1 mg/mL


ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000



NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.


Gene Information

human ... GFAP(2670)

General description

Glial fibrillary acidic protein (GFAP) is an intermediate-filament protein found in the astrocytes of CNS (central nervous system). It is located on human chromosome 17q21.
Anti-GFAP Antibody detects endogenous levels of total GFAP protein.


The antiserum was produced against synthesized peptide derived from human GFAP.

Immunogen Range: 11-60


Anti-GFAP, N-Terminal antibody has been used in immunocytochemical analysis , confocal and fluorescent microscopic imaging , immunostaining and western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem/physiol Actions

Glial fibrillary acidic protein (GFAP) regulates intermediate filament network dynamics, cell morphology and focal adhesions.It helps in maintaining myelination and stability of CNS (central nervous system) white matter architecture.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke
Tseng KY, et al.
Molecular Therapy (2017)
GFAP promoter directs astrocyte-specific expression in transgenic mice
Brenner M, et al.
The Journal of Neuroscience (1994)
Childhood constipation; an overview of genetic studies and associated syndromes
Peeters B, et al.
Best Practice & Research. Clinical Gastroenterology, 25 (2011)
GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination
Liedtke W, et al.
Neuron, 17, 607-615 (1996)
Suppression of agrin-22 production and synaptic dysfunction in Cln1 (-/-) mice
Peng S, et al.
Annals of Clinical and Translational Neurology, 2, 1085-1104 (2015)

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