Skip to Content
MilliporeSigma

SAB4502584

Anti-Retinoblastoma, C-Terminal antibody produced in rabbit

affinity isolated antibody

Synonym(s):

P105-RB, PP105, PP110, RB-1, RB1

Slide 1 of 2
Sign In to View Organizational & Contract Pricing.

Select a Size

100 μG

$560.00

$560.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00282455
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC
Citations:
4

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 106 kDa

species reactivity

mouse, human, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100

NCBI accession no.

P06400

UniProt accession no.

P06400

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... RB1(5925)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
SAB4502590SAB1305398R4278
Anti-Retinoblastoma, C-Terminal antibody produced in rabbit affinity isolated antibody

Sigma-Aldrich

SAB4502584

Anti-Retinoblastoma, C-Terminal antibody produced in rabbit

Anti-Retinoblastoma antibody produced in rabbit affinity isolated antibody

Sigma-Aldrich

SAB4502590

Anti-Retinoblastoma antibody produced in rabbit

ANTI-PHOSPHO-RB(S612) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

SAB1305398

ANTI-PHOSPHO-RB(S612) antibody produced in rabbit

Anti-phospho-Retinoblastoma (pSer811) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

R4278

Anti-phospho-Retinoblastoma (pSer811) antibody produced in rabbit

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

species reactivity

mouse, human, rat

species reactivity

human, rat, mouse

species reactivity

human

species reactivity

rat, mouse, human

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−70°C

General description

The gene encoding Retinoblastoma-associated protein (RB1) is a tumor suppressor gene localized on human chromosome 13q14.2. Anti-Retinoblastoma Antibody detects endogenous levels of total Retinoblastoma protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human Retinoblastoma.

Immunogen Range: 791-840

Biochem/physiol Actions

Retinoblastoma-associated protein (RB1) modulates the cell cycle. It acts as a repressor of transcription mediated by E2 factor (E2F) and influences transcriptional silencing. RB1 modulates mitochondrial activities and has a role in the organisation of heterochromatin. Mutations in the gene encoding this protein have been associated with childhood retinoblastoma.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
210811

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Frequent deletions at 11q23 and 13q14 in B cell prolymphocytic leukemia (B-PLL).
Lens D
Leukemia, 14(3), 427-430 (2000)
Saeeda Kalsoom et al.
Molecular vision, 21, 1085-1092 (2015-09-24)
Retinoblastoma (RB) is a rare intraocular malignant tumor of the developing retina with an estimated incidence of 1:20,000 live births in children under the age of 5 years. In addition to the abnormal whitish appearance of the pupil or leukocoria
Deficiencies in Cellular Processes Modulated by the Retinoblastoma Protein Do Not Account for Reduced Human Cytomegalovirus Replication in Its Absence.
VanDeusen HR and Kalejta RF
Journal of Virology, 89(23), 11965-11974 (2015)
Halena R VanDeusen et al.
Journal of virology, 89(9), 5012-5021 (2015-02-20)
The retinoblastoma (Rb) tumor suppressor controls cell cycle, DNA damage, apoptotic, and metabolic pathways. DNA tumor virus oncoproteins reduce Rb function by either inducing Rb degradation or physically disrupting complexes between Rb and its myriad binding proteins. Human cytomegalovirus (HCMV)

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service