SAB4502857

Anti-SRPK1 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): SFRS protein kinase 1, SR-protein-specific kinase 1, Serine/arginine-rich protein-specific kinase 1

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 92 kDa
• species reactivity: rat, mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:40000; western blot: 1:500-1:1000
• NCBI accession no.: Q96SB4
• UniProt accession no.: Q96SB4
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... SRPK1(6732)

Description

General description

Anti-SRPK1 Antibody detects endogenous levels of total SRPK1 protein.
Serine-arginine protein kinase 1 (SRPK1) belongs to the SR kinase family. In mammals, SRPK1 is expressed in the central nervous system in a region- and neuron-specific manner. This gene is mapped to human chromosome 6p21.2-p21.3. SRPK1 is also expressed in several normal tissues like testis and pancreas.

Immunogen

The antiserum was produced against synthesized peptide derived from human SRPK1.

Immunogen Range: 521-570

Biochem/physiol Actions

Serine-arginine protein kinase 1 (SRPK1) modulates angiogenesis. Suppressing SRPK1 prevents the development and migration in renal carcinoma cells. In normoxic condition, SRPK1 can increase the migration and invasion of glioma cells.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable