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Anti-Vitamin D Receptor antibody produced in rabbit

affinity isolated antibody

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1,25-dihydroxyvitamin D3 receptor, NR1I1, vitamin D receptor, vitamin D3 receptor
MDL number:

biological source


Quality Level



antibody form

affinity isolated antibody

antibody product type

primary antibodies




buffered aqueous solution

mol wt

antigen 48 kDa

species reactivity



~1 mg/mL


ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.


target post-translational modification


Gene Information

human ... VDR(7421)

General description

Anti-Vitamin D Receptor Antibody detects endogenous levels of total Vitamin D Receptor protein.
Vitamin D receptor (VDR) gene codes for a nuclear receptor. It is expressed at a high level in the hypothalamus and the large neurons of the substantia nigra in the brain. VDR gene comprises 14 exons and 6 untranslated exons with alternative splicing sites. It is mapped to human chromosome 12q13.1.


The antiserum was produced against synthesized peptide derived from human Vitamin D Receptor.

Immunogen Range: 181-230


Anti-Vitamin D Receptor antibody produced in rabbit has been used in western blotting and immunofluorescence staining (1:200) (1:100).

Biochem/physiol Actions

Vitamin D receptor (VDR) protein modulates genes associated with inflammation, chronic diseases, oxidative damage, and the metabolism of bone. VDR gene is involved in the susceptibility of type 2 diabetes mellitus (T2DM). The nuclear receptor encoded by the VDR gene possesses pluripotent effects. It is capable of specifically binding the elements of DNA response when bound to the ligand. VDR acts as a receptor for 1,25 dihydroxyvitamin D3 (1,25(OH)2 D3). It facilitates the biological activities of vitamin D. Inadequacy of vitamin D is a risk factor for Alzheimer′s disease (AD).

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids




Not applicable


Not applicable

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