CDH1 (cadherin 1) codes for a transmembrane glycoprotein E-cadherin that is located on human chromosome 16q22.1. It is a tumor suppressor gene, which is also known as Cdh1p/Hct1p, Fizzy-related, Ste9, or Srw1.
Anti-E-cadherin Antibody detects endogenous levels of total E-cadherin protein.
The antiserum was produced against synthesized peptide derived from human E-cadherin.
Immunogen Range: 1-50
Anti-E-cadherin, N-Terminal antibody has been used in protein extraction,western blotting, confocal fluorescence microscopy analysis, immunostaining and co-immunoprecipitation.
CDH1 (cadherin 1) helps to conserve the homophilic cell-cell adhesion in epithelial tissues. Inadequate expression of CDH1 results in colon cancer and renal cell carcinoma (RCC).
Features and Benefits
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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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