MilliporeSigma
All Photos(1)

Documents

SAB4700094

Sigma-Aldrich

Monoclonal Anti-CD9-Biotin antibody produced in mouse

clone MEM-61, purified immunoglobulin, buffered aqueous solution

Sign Into View Organizational & Contract Pricing

Select a Size

NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

biotin conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

MEM-61, monoclonal

form

buffered aqueous solution

species reactivity

human

concentration

1 mg/mL

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... CD9(928)

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
SAB4700092SAB4700075SAB4700504
conjugate

biotin conjugate

conjugate

unconjugated

conjugate

unconjugated

conjugate

biotin conjugate

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

clone

MEM-61, monoclonal

clone

MEM-61, monoclonal

clone

MEM-98, monoclonal

clone

MEM-108, monoclonal

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

General description

Cluster of differentiation 9 (CD 9) molecule, a member of transmembrane 4 super family (TM4SF) or tetraspanin superfamily, possesses four transmembrane domain. In human chromosome, the gene CD9 is localized on 12p13.31. The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.

Immunogen

Pre-B cell line NALM-6

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1:400. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Biochem/physiol Actions

Functions of cluster of differentiation 9 (CD9) molecule (CD9) include cell proliferation, activation, motility, and metastasis of tumor cells. CD9 along with CD81 is implicated to play a key role in muscle cell fusion and myotube maintenance. CD9 is associated with Interleukin 16 (IL-16) and induces migration and activation of mast cells. CD9 is involved in megakaryopoiesis. CD9 is expressed in Cord Blood CD34+ cells and might play a key role in hematopoietic stem cell (HSC) homing. CD9 associates with β1 integrin, membrane type 1−matrix metalloproteinase (MT1-MMP) and CD26 for HSC motility and homing. CD9 is crucial for sperm-egg fusion during fertilization. CD9 is a key molecule for glycoprotein 130 (gp130) mediated tumorigenic signal transduction in glioblastoma and a potential target for therapy.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Genomic deletion of chromosome 12p is an independent prognostic marker in prostate cancer
Kluth M, et al.
Oncotarget, 6(29), 27966-27979 (2015)
The gamete fusion process is defective in eggs of Cd9-deficient mice
Kaji K, et al.
Nature Genetics, 24(3), 279-282 (2000)
The tetraspanin CD9 regulates migration, adhesion, and homing of human cord blood CD34+ hematopoietic stem and progenitor cells
Leung KT, et al.
Blood, 117(6), 1840-1850 (2011)
CD9 and megakaryocyte differentiation
Clay D, et al.
Blood, 97(7), 1982-1989 (2001)
Role of transmembrane 4 superfamily (TM4SF) proteins CD9 and CD81 in muscle cell fusion and myotube maintenance
Tachibana I and Hemler ME
The Journal of Cell Biology, 146(4), 893-904 (1999)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service