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Monoclonal Anti-CDH1 antibody produced in mouse

clone 67A4, purified immunoglobulin, buffered aqueous solution

Anti-CD324, Anti-E-CADHERIN

Quality Level

biological source


antibody form

purified immunoglobulin

antibody product type

primary antibodies


67A4, monoclonal


buffered aqueous solution

species reactivity



1 mg/mL


flow cytometry: suitable





NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.


Gene Information

human ... CDH1(999)

General description

CDH1 (cadherin 1) codes for a transmembrane glycoprotein E-cadherin that is located on human chromosome 16q22.1. It is a tumor suppressor gene, which is also known as Cdh1p/Hct1p, Fizzy-related, Ste9, or Srw1.


T-47D cells


The reagent is designed for Flow Cytometry analysis using 5-10 μg reagent / 1e6 cells in a suspension.

Biochem/physiol Actions

CDH1 (cadherin 1) helps to conserve the homophilic cell-cell adhesion in epithelial tissues. Inadequate expression of CDH1 results in colon cancer and renal cell carcinoma (RCC).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

CDH1 promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer.
Caldeira JRF, et al.
BMC Cancer, 6(1), 48-48 (2006)
Reduced E-cadherin facilitates renal cell carcinoma progression by WNT/?-catenin signaling activation
Zhang X, et al.
Oncotarget, 8(12), 19566-19576 (2017)
Mitotic regulation of the APC activator proteins CDC20 and CDH1
Kramer ER, et al.
Molecular Biology of the Cell, 11(5), 1555-1569 (2000)
Judith Wenzina et al.
The Journal of investigative dermatology, 140(4), 878-890 (2019-10-18)
Melanoma cells can switch between distinct gene expression profiles, resulting in proliferative or invasive phenotypes. Signaling pathways involved in this switch were analyzed by gene expression profiling of a cohort of 22 patient-derived melanoma cell lines. CDH1 negativity was identified...
Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells
Chen J, et al.
Oncotarget, 8(12), 19609-19630 (2017)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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