SAB4701098

Monoclonal Anti-CD3-APC antibody produced in mouse

clone APA1/1

• Synonym(s): CD3 epsilon chain, CD3epsilon, IMD18, T3E
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• conjugate: Allophycocyanin conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: APA1/1, monoclonal
• form: buffered aqueous solution
• concentration: 0.1 mg/mL
• technique(s): flow cytometry: 1.5 μg/mL
• accession no.: BC049847
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: human ... CD3E(916)

Description

General description

The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.

Immunogen

Purified human CD3 proteins isolated from thymus

Physical form

Solution in phosphate buffered saline with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable