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SAB5300225

Sigma-Aldrich

Monoclonal Anti-PIK3CA antibody produced in mouse

clone 4F3, purified immunoglobulin, buffered aqueous solution

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Synonym(s):
PI3K, p110-alpha

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4F3, monoclonal

form

buffered aqueous solution

mol wt

124 kDa

species reactivity

human

technique(s)

direct ELISA: 1:10,000
flow cytometry: 1:200-1:400
indirect immunofluorescence: 1:200-1:1,000
western blot: 1:500-1:2,000

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PIK3CA(5290)

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This Item
WH0005290M1AMAB91514AMAB91513
conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

clone

4F3, monoclonal

clone

3G3, monoclonal

clone

CL8347, monoclonal

clone

CL8345, monoclonal

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

mol wt

124 kDa

mol wt

-

mol wt

-

mol wt

-

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Immunogen

Purified recombinant fragment of human PIK3CA expressed in E.coli.
Mouse monoclonal antibody raised against PIK3CA

Physical form

Purified antibody in PBS with 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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25G
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705578-5MG-PW

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1000309185

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Hong Lu et al.
Oncology letters, 17(1), 69-72 (2019-01-19)
The expression pattern of tumor suppressor gene phosphatase and tensin homolog deleted on chromosome ten (PTEN) and phosphatase and tensin homolog deleted on chromosome ten/phosphatidylinositol3-kinase/protein kinase B (PTEN/PI3K/AKT) cell signaling pathway in renal cell carcinoma (RCC) were investigated in children.
Zhi Teng et al.
Oncology reports, 43(2), 503-515 (2020-01-03)
Acute lymphoblastic leukemia (ALL) is a malignant hematological disease. Tanshinone IIA (Tan IIA) has antitumor activity in vitro and in vivo. The aim of the present study was to investigate the effects of Tan IIA in combination with imatinib (IM) on the proliferation, apoptosis, migration

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