SAB5500074

Sigma-Aldrich

Anti-CD8 antibody, Rabbit monoclonal

recombinant, expressed in proprietary host, clone SP16, tissue culture supernatant

NACRES:
NA.41

biological source

rabbit

Quality Level

recombinant

expressed in proprietary host

antibody form

tissue culture supernatant

antibody product type

primary antibodies

clone

SP16, monoclonal

species reactivity

human (tested)

application(s)

immunohistochemistry: 1:100

isotype

IgG

conjugate

unconjugated

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... CD8A(925)

General description

CD8 molecule consists of two chains, termed α and β chain, which are expressed as a disulphide-linked α/β heterdimer or as an α/α homodimer on T cell subset, thymocytes and NK cells. The majority of CD8+ T cells express CD8 as α/β heterdimer. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 α chain (but not β chain).

Immunogen

Synthetic peptide corresponding to C-terminus of alpha chain of the human CD8 molecule.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Barbara Ludwig et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(44), 11745-11750 (2017-10-29)
Transplantation of pancreatic islets for treating type 1 diabetes is restricted to patients with critical metabolic lability resulting from the need for immunosuppression and the shortage of donor organs. To overcome these barriers, we developed a strategy to macroencapsulate islets...

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