SAB5500187

Sigma-Aldrich

Anti-Thyroid Transcription Factor-1 antibody, Rabbit monoclonal

clone SP141, recombinant, expressed in proprietary host, affinity isolated antibody

NACRES:
NA.41

biological source

rabbit

Quality Level

recombinant

expressed in proprietary host

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

SP141, monoclonal

species reactivity

human (tested)

species reactivity (predicted by homology)

rat, mouse

application(s)

flow cytometry: 1:100
immunohistochemistry: 1:100

isotype

IgG

conjugate

unconjugated

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... NKX2-1(7080)

General description

Thyroid transcription factor-1 (TTF-1), also known as NK2 homeobox 1(NKX2-1), is a member of the NKx2 family of homeodomain transcription factors. It binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. TTF-1 is expressed in epithelial cells of the thyroid gland and the lung, and their derived tumors such as lung adenocarcinoma and small cell carcinomas and thyroid cancer. It is absent in mesotheliomas, breast cancer, and colon cancer.

Immunogen

Synthetic peptide derived from the internal region of human TTF-1 protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin

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