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SAB5600114

Sigma-Aldrich

Anti-CD140b (PDGF Receptor beta)antibody, Rabbit Monoclonal

recombinant, expressed in HEK 293 cells, clone RM303, purified immunoglobulin

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Synonym(s):
Platelet-derived growth factor receptor beta
NACRES:
NA.41

recombinant

expressed in HEK 293 cells

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

RM303, monoclonal
recombinant monoclonal

form

buffered aqueous glycerol solution

species reactivity

human

technique(s)

immunohistochemistry: 1:500-1:1000
western blot: 1:250-1:500

isotype

IgG

NCBI accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PDGFRB(5159)

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This Item
SAB4502148SAB4502149SAB5700369
antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

Gene Information

human ... PDGFRB(5159)

Gene Information

human ... PDGFRB(5159)

Gene Information

human ... PDGFRB(5159)

Gene Information

human ... PDGFRB(5159)

species reactivity

human

species reactivity

mouse, human, rat

species reactivity

rat, mouse, human

species reactivity

human, mouse

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

isotype

IgG

isotype

-

isotype

-

isotype

-

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General description

The PDGFRB (platelet derived growth factor receptor β) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.

Specificity

This antibody reacts to human CD140b (PDGFR-beta) (Platelet-derived growth factor receptor beta).

Immunogen

A peptide corresponding to the C-terminus of human CD140b.

Biochem/physiol Actions

PDGFRB (platelet derived growth factor receptor β) acts as a regulator of mesenchymal cells in tumour cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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