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SAB5700062

Sigma-Aldrich

Anti-ATG5 antibody produced in rabbit

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Synonym(s):
APG5, APG5-LIKE, APG5L, ASP, ATG5, hAPG5

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

22
32

species reactivity

mouse, rat, human

concentration

0.85mg/ml

technique(s)

immunofluorescence: 1:50-1:200
western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ATG5(9474)

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This Item
SAB2108076HPA042973SAB5701331
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

-

species reactivity

mouse, rat, human

species reactivity

mouse, guinea pig, rat, horse, dog, rabbit, human, bovine

species reactivity

human

species reactivity

rat, human, mouse

UniProt accession no.

Q9H1Y0

UniProt accession no.

Q9H1Y0

UniProt accession no.

Q9H1Y0

UniProt accession no.

Q9H1Y0

technique(s)

immunofluorescence: 1:50-1:200, western blot: 1:500-1:2000

technique(s)

immunoblotting: suitable, immunohistochemistry: suitable

technique(s)

immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:50-1:200

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

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General description

The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human ATG5 (NP_004840.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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