SAB5700285

Anti-Phospho-CDK1-T14 antibody produced in rabbit

• Synonym(s): CDC2, CDC28A, CDK1, P34CDC2
• NACRES: NA.41
• UNSPSC Code: 12352203
• Clone: polyclonal
• Species reactivity: rat, mouse, human
• Application: IF, WB
• Citations: -

Properties

• biological source: rabbit
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 27, 34
• species reactivity: rat, mouse, human
• concentration: 1.56 mg/ml
• technique(s): immunofluorescence: 1:50-1:100, western blot: 1:500-1:1000
• UniProt accession no.: P06493
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pThr14)
• Quality Level: 100
• Gene Information: human ... CDK1(983)

Description

General description

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around T14 of human CDK1 (NP_001777.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable