SAB5700348

Anti-Phospho-FAK-Y397 antibody produced in rabbit

• Synonym(s): FADK, FAK, FAK1, FRNK, PPP1R71, PTK2, p125FAK, pp125FAK
• NACRES: NA.43
• UNSPSC Code: 12352203

Properties

• mol wt: 99; 114; 119; 120; 39; 48; 63
• biological source: rabbit
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: mouse, human, rat
• concentration: 0.99 mg/ml
• technique(s): western blot: 1:500-1:1000
• UniProt accession no.: Q05397
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr397)
• Quality Level: 100
• Gene Information: human ... PTK2(5747)

Description

General description

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around Y397 of human FAK (NP_722560.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable