SAB5700432

Anti-Phospho-IκBα-S32/36 antibody produced in rabbit

• Synonym(s): EDAID2, IKB alpha, IKBA, MAD-3, NFKBI, NFKBIA
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 35
• species reactivity: human, mouse
• concentration: 0.54 mg/ml
• technique(s): western blot: 1:500-1:1000
• UniProt accession no.: P25963
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer32/pSer36)
• Gene Information: human ... NFKBIA(4792)

Description

General description

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Immunogen

A synthetic phosphorylated peptide around S32 & S36 of human IκBα (NP_065390.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable