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SAB5701276

Sigma-Aldrich

Anti-Dysferlin (Romeo) antibody produced in rabbit

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biological source

rabbit

Quality Level

antibody product type

primary antibodies

clone

monoclonal

form

liquid

species reactivity

rat, human, mouse

concentration

0.85 mg/mL

technique(s)

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DYSF(8291)

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This Item
SAB4503260SAB4200388SAB5700963
clone

monoclonal

clone

polyclonal

clone

polyclonal

clone

monoclonal

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

Gene Information

human ... DYSF(8291)

Gene Information

human ... DYSF(8291)

Gene Information

human ... DYSF(8291)
mouse ... Dysf(26903)

Gene Information

human ... MB(4151)

UniProt accession no.

O75923

UniProt accession no.

O75923

UniProt accession no.

O75923

UniProt accession no.

P02144

shipped in

wet ice

shipped in

wet ice

shipped in

dry ice

shipped in

wet ice

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General description

The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008]

Immunogen

A synthesized peptide derived from human Dysferlin (Romeo)

Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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