SAB5701295

Anti- Cleaved PARP1 p25 antibody produced in rabbit

• NACRES: NA.43
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: monoclonal
• Application: IHC, WB
• Citations: -

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody product type: primary antibodies
• clone: monoclonal
• form: liquid
• species reactivity: human, mouse, rat
• concentration: 0.33 mg/mL
• technique(s): immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000
• UniProt accession no.: P09874
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... PARP1(142)

Description

General description

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

Immunogen

A synthesized peptide derived from human Cleaved PARP1 p25.

Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable