SAB5701591

Anti-LDHB antibody produced in rabbit

• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: monoclonal
• Application: IHC, WB
• Citations: -

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody product type: primary antibodies
• clone: monoclonal
• form: liquid
• species reactivity: rat, human, mouse
• concentration: 0.85 mg/mL
• technique(s): immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000
• UniProt accession no.: P07195
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Quality Level: 100
• Gene Information: human ... LDHB(3945)

Description

General description

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]

Immunogen

A synthesized peptide derived from human LDHB

Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable