SAB5701596

Anti-GLUD1 antibody produced in rabbit

• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: monoclonal
• Application: immunohistochemistry; western blot
• Species reactivity: mouse, rat, human
• Technique(s): immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• Uniprot accession no.: P00367

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody product type: primary antibodies
• clone: monoclonal
• form: liquid
• species reactivity: mouse, rat, human
• concentration: 0.51 mg/mL
• technique(s): immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProt accession no.: P00367
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Quality Level: 100
• Gene Information: human ... GLUD1(2746)

Description

General description

This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]

Immunogen

A synthesized peptide derived from human GLUD1

Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable