SBR00015

AEBSF Ready Made Solution

• Synonym(s): 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
• Empirical Formula (Hill Notation): C₈H₁₀FNO₂S · HCl
• CAS Number: 30827-99-7
• Molecular Weight: 239.69
• MDL number: MFCD00132962
• UNSPSC Code: 12352202
• NACRES: NA.85

Properties

• assay: ≥97%
• Quality Level: 200
• form: liquid
• storage condition: protect from light
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: F[S](=O)(=O)c1ccc(cc1)CCN.[Cl-].[H+]
• InChI: 1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H
• InChI key: WRDABNWSWOHGMS-UHFFFAOYSA-N

Description

Application

This solution is provided at 100 mM in water. The stock solution may be diluted 1:100 for a 1 mM working concentration. Recommended concentrations for use are 0.1-1.0 mM.

Biochem/physiol Actions

AEBSF is a specific irreversible serine protease inhibitor. It inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. AEBSF is an excellent alternative to available serine protease inhibitors as it offers superior inhibitory activity and much lower toxicological risk.

Other Notes

The stability of AEBSF decreases rapidly at higher temperatures and at a pH greater than 7.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable