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  • SBR00067
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SBR00067

Sigma-Aldrich

Rifampicin Water Soluble

solubility: 50 mg/mL in water, freely soluble

form

solid

Quality Level

specific activity

(Antibacterial)

solubility

water: freely soluble 50 mg/mL

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
mycobacteria
viruses

Mode of action

protein synthesis | interferes

storage temp.

−20°C

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H0396C3175N6803
Sigma-Aldrich

Sigma-Aldrich

N6803

Nystatin water soluble

form

solid

form

crystalline

form

powder

form

powder

specific activity

(Antibacterial)

specific activity

-

specific activity

-

specific activity

-

solubility

water: freely soluble 50 mg/mL

solubility

H2O: 400 mg/mL

solubility

H2O: 50-500 mg/mL (stock solution), PBS: 50-500 mg/mL (stock solution), other salt solutions: not recommended

solubility

100 mg/mL

antibiotic activity spectrum

Gram-negative bacteria

antibiotic activity spectrum

-

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, mycobacteria, mycoplasma

antibiotic activity spectrum

-

mode of action

protein synthesis | interferes

mode of action

-

mode of action

protein synthesis | interferes

mode of action

-

storage temp.

−20°C

storage temp.

room temp

storage temp.

-

storage temp.

−20°C

General description

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. Rifampicin is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, and primary biliary cirrhosis (PBC). Rifampicin was also found active by inhibiting Tau Oligomer Propagation in Alzheimer’s disease. In addition, Rifampicin is used as a selection agent for agrobacterium mediated plant transformation.

Application

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis.

Biochem/physiol Actions

Rifampicin inhibits the assembly of DNA and protein into mature virus particles. It inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase, which results in cell death.

Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase. Inhibits the assembly of DNA and protein into mature virus particles.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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