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SCP0101

Sigma-Aldrich

Caspase Substrate

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Empirical Formula (Hill Notation):
C35H40N6O11
Molecular Weight:
720.73
NACRES:
NA.32

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥80%

storage condition

protect from light

storage temp.

−20°C

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SCP0066SCP0084SCP0105
Sigma-Aldrich

SCP0101

Caspase Substrate

Sigma-Aldrich

SCP0066

Caspase 1 Substrate

Sigma-Aldrich

SCP0084

Caspase 3 Substrate

Sigma-Aldrich

SCP0105

Caspase Substrate, chromogenic

form

lyophilized

form

lyophilized

form

lyophilized

form

lyophilized

storage condition

protect from light

storage condition

protect from light

storage condition

protect from light

storage condition

protect from light

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

composition

Peptide Content, ≥80%

composition

Peptide Content, ≥80%

composition

Peptide Content, ≥80%

composition

Peptide Content, ≥75%

Amino Acid Sequence

Z-Tyr-Val-Ala-Asp-pNA

Application

Z-YVAD-pNa (Z-Tyr-Val-Ala-Asp-pNA) is used as a caspase 1 substrate.

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A Eckert et al.
Journal of neuroscience research, 64(2), 183-192 (2001-04-05)
The Swedish double mutation (KM670/671NL) of amyloid precursor protein (APPsw) is associated with early-onset familial Alzheimer's disease (FAD) and results in from three- to sixfold increased beta-amyloid production. The goal of the present study was to elucidate the effects of
G P McStay et al.
Cell death and differentiation, 15(2), 322-331 (2007-11-03)
Caspases orchestrate the controlled demise of a cell after an apoptotic signal through specific protease activity and cleavage of many substrates altering protein function and ensuring apoptosis proceeds efficiently. Comparing a variety of substrates of each apoptotic caspase (2, 3
Natasha Ann Pereira et al.
Biochemical and biophysical research communications, 377(3), 873-877 (2008-11-04)
Many designated substrates and inhibitors have been widely used to investigate the roles of caspases in apoptotic death during mammalian cell culture. However, the specificities of these substrates and inhibitors have not been systematically evaluated. As a result, conclusions on

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