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SCP0105

Sigma-Aldrich

Caspase Substrate, chromogenic

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Empirical Formula (Hill Notation):
C31H43N9O14
Molecular Weight:
765.73
NACRES:
NA.32

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

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SCP0105

Caspase Substrate, chromogenic

Sigma-Aldrich

SCP0091

Caspase 9 Substrate, chromogenic

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SCP0101

Caspase Substrate

Sigma-Aldrich

SCP0107

Caspase1 Substrate

form

lyophilized

form

lyophilized

form

lyophilized

form

lyophilized

storage condition

protect from light

storage condition

protect from light

storage condition

protect from light

storage condition

protect from light

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

composition

Peptide Content, ≥75%

composition

Peptide Content, ≥75%

composition

Peptide Content, ≥80%

composition

Peptide Content, ≥85%

Amino Acid Sequence

Ac-Val-Asp-Gln-Gln-Asp-pNA

Application

Ac-VDQQD-pNA (acetyl-Val-Asp-Gln-Gln-Asp-p-nitroanilide) is used as a chromogenic caspase substrate.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Gary K Smith et al.
Archives of biochemistry and biophysics, 399(2), 195-205 (2002-03-13)
Because of the intimate role of caspase-8 in apoptosis signaling pathways from FAS, TNFR1, and other death receptors, the enzyme is a potentially important therapeutic target. We have generated an Escherichia coli expression construct for caspase-8 in which a His-tag
Vasoactive intestinal peptide inhibits TNF-α-induced apoptotic events in acinar cells from nonobese diabetic mice submandibular glands.
Calafat M, Larocca L, Roca V, Hauk V, et al.
Arthritis Research, 11, R53-R53 (2009)
Natasha Ann Pereira et al.
Biochemical and biophysical research communications, 377(3), 873-877 (2008-11-04)
Many designated substrates and inhibitors have been widely used to investigate the roles of caspases in apoptotic death during mammalian cell culture. However, the specificities of these substrates and inhibitors have not been systematically evaluated. As a result, conclusions on

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