SMB00149

Quercetin 3-glucuronide

≥95% (LC/MS-ELSD)

• Synonym(s): Quercetin 3-glucuronide, Quercetol 3-O-glucuronide, Quercetol glucuronide, Querciturone, 3,3′,4′,5,7-Pentahydroxyflavone 3-glucuronide, Mikwelianin, Miquelianin, Quercetin 3-O-β-D-glucuronide
• Empirical Formula (Hill Notation): C₂₁H₁₈O₁₃
• CAS Number: 22688-79-5
• Molecular Weight: 478.36
• NACRES: NA.25
• PubChem Substance ID: 329824823
• UNSPSC Code: 12352205
• MDL number: MFCD09752939

Properties

• storage temp.: −20°C
• Quality Level: 200
• InChI: 1S/C21H18O13/c22-7-4-10(25)12-11(5-7)32-17(6-1-2-8(23)9(24)3-6)18(13(12)26)33-21-16(29)14(27)15(28)19(34-21)20(30)31/h1-5,14-16,19,21-25,27-29H,(H,30,31)/t14-,15-,16+,19-,21+/m0/s1
• SMILES string: O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4
• InChI key: DUBCCGAQYVUYEU-ZUGPOPFOSA-N
• assay: ≥95% (LC/MS-ELSD)
• form: solid
• application(s): metabolomics; vitamins, nutraceuticals, and natural products

Description

Biochem/physiol Actions

Quercetin 3-glucuronide might reduce the risk of developing Alzheimer′s disease dementia. It is found to prevent the formation of β-amyloid (Aβ) peptides in mouse model.[1] Quercetin 3-glucuronide is a metabolic product of dietary quercetin, which occurs in intestinal mucosa and liver. Quercetin 3-glucuronide possess antioxidant activity and is known to have a protective action on LDL (low density lipoprotein) oxidation.[2]

General description

Quercetin 3-glucuronide is a natural product derived from a plant source. Quercetin is an important flavonoid present in most of the vegetables including onion.[2] It is one of the polyphenol metabolites that is found to be localized to the brain.[1]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable