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SML0107

Sigma-Aldrich

Pemirolast potassium

≥98% (HPLC)

Synonym(s):
9-Methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one potassium salt; BMY 26517
Empirical Formula (Hill Notation):
C10H7N6O·K
CAS Number:
Molecular Weight:
266.30
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥98% (HPLC)

form

powder

color

light yellow to green-yellow

solubility

H2O: ≥18 mg/mL

originator

Bristol-Myers Squibb

storage temp.

2-8°C

SMILES string

[K+].CC1=CC=CN2C(=O)C(=CN=C12)c3nnn[n-]3

InChI

1S/C10H7N6O.K/c1-6-3-2-4-16-9(6)11-5-7(10(16)17)8-12-14-15-13-8;/h2-5H,1H3;/q-1;+1

InChI key

NMMVKSMGBDRONO-UHFFFAOYSA-N

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Pemirolast potassium is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent. It Inhibits chemical mediator release from tissue mast cells and has recently also been shown to inhibit the release of peptides including substance P, neurokinin (NK) A, and calcitonin gene-related peptide (CGRP) from sensory nerves. It has been used for the treatment of allergic conjunctivitis prophylaxis of for pulmonary hypersensitivity reactions to drugs such as paclitaxel

Features and Benefits

This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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