SML0412

IM-54

≥98% (HPLC)

• Synonym(s): 1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione, 2-(1H-Indol-3-yl)-3-pentylamino-maleimide
• Empirical Formula (Hill Notation): C₁₉H₂₃N₃O₂
• CAS Number: 861891-50-1
• Molecular Weight: 325.40
• MDL number: MFCD18382109
• PubChem Substance ID: 329825407
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: light orange to dark orange
• solubility: DMSO: 5 mg/mL (clear solution)
• storage temp.: 2-8°C
• SMILES string: CCCCCNC1=C(C(=O)N(C)C1=O)c2cn(C)c3ccccc23
• InChI: 1S/C19H23N3O2/c1-4-5-8-11-20-17-16(18(23)22(3)19(17)24)14-12-21(2)15-10-7-6-9-13(14)15/h6-7,9-10,12,20H,4-5,8,11H2,1-3H3
• InChI key: SGLOMINNEBLJFF-UHFFFAOYSA-N

Description

Biochem/physiol Actions

IM-54 is a cell permeable, potent and selective inhibitor of necrosis. The compound inhibits necrosis induced by oxidative stress. IM-54 does not inhibit apoptosis induced by anticancer drugs.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable