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SML0446

Sigma-Aldrich

A-419259 trihydrochloride

≥98% (HPLC)

Synonym(s):

7-[Trans-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride, A419259 trihydrochloride

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$213.00
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$894.00

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5 MG
$213.00
25 MG
$894.00

About This Item

Empirical Formula (Hill Notation):
C29H34N6O · 3HCl
CAS Number:
Molecular Weight:
592.00
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

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$213.00


In StockDetails


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Quality Level

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 10 mg/mL (clear solution)

storage temp.

room temp

SMILES string

Cl.Cl.Cl.CN1CCN(CC1)[C@H]2CC[C@@H](CC2)n3cc(-c4ccc(Oc5ccccc5)cc4)c6c(N)ncnc36

InChI

1S/C29H34N6O.3ClH/c1-33-15-17-34(18-16-33)22-9-11-23(12-10-22)35-19-26(27-28(30)31-20-32-29(27)35)21-7-13-25(14-8-21)36-24-5-3-2-4-6-24;;;/h2-8,13-14,19-20,22-23H,9-12,15-18H2,1H3,(H2,30,31,32);3*1H/t22-,23-;;;

InChI key

ALRMEQIQFCUAMR-KOONDFAVSA-N

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This Item
SML0276PZ0100SML1332
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

solubility

H2O: 10 mg/mL (clear solution)

solubility

H2O: >15 mg/mL

solubility

DMSO: 10 mg/mL, clear

solubility

H2O: 5 mg/mL, clear

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated

storage condition

protect from light

Biochem/physiol Actions

A-419259 is a potent inhibitor of Src family kinases.
A-419259 is a potent inhibitor of Src family kinases. IC50 values for src, lck, blk, csk, fyn and lyn range between 15 and 50 nM.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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