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SML0629

Sigma-Aldrich

Mitochondrial Fusion Promoter M1

≥95% (HPLC)

Synonym(s):

(E)-4-Chloro-2-(1-(2-(2,4,6-trichlorophenyl)hydrazono)ethyl)phenol, 1-(5-Chloro-2-hydroxyphenyl)-ethanone 2-(2,4,6-trichlorophenyl)hydrazone

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25 MG
$162.45

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25 MG
$162.45

About This Item

Empirical Formula (Hill Notation):
C14H10Cl4N2O
CAS Number:
Molecular Weight:
364.05
UNSPSC Code:
12352200
NACRES:
NA.77

$162.45

List Price$171.00Save 5%
Web-Only Promotion

In StockDetails


Request a Bulk Order

assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

Clc1c(c(cc(c1)Cl)Cl)NNC(=C)c2c(ccc(c2)Cl)O

InChI key

WMAGOVJOXMBLHY-UHFFFAOYSA-N

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Show Differences

1 of 4

This Item
SML2738SML2739SML1762
SM1-71 ≥98% (HPLC)

SML2738

SM1-71

SM1-71-R ≥98% (HPLC)

SML2739

SM1-71-R

SI-2 ≥98% (HPLC)

SML1762

SI-2

form

powder

form

powder

form

powder

form

powder

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

, light yellow to dark orange

Application

Mitochondrial Fusion Promoter M1 has been used as a fusion promoter:
  • to study its effects on peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α expression in breast cancer cells[1]
  • to study the link between nucleoside diphosphate kinase 3 (NME3)-regulated mitochondrial fluctuations and stability of genome in NME3 knockdown cells[2]
  • to study its effects on mitochondrial fusion in neuronal cells[3]

Biochem/physiol Actions

Mitochondrial Fusion Promoter M1 is a cell permeable hydrazone that enhances mitochondrial fusion.
Mitochondrial Fusion Promoter M1 is a cell permeable hydrazone that enhances mitochondrial fusion. M1 protects cells from mitochondrial fragmentation associated cell death. Mitochondrial Fusion Promoter M1 does not interfere with endoplasmic reticula (ER) and lysosomes morphology.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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