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SML1141

Sigma-Aldrich

Solasodine

≥95% (HPLC)

Synonym(s):

(-)-Solasodine, (3β,22α,25R)-Spirosol-5-en-3-ol, NSC 178260, NSC 179187, Purapuridine, Solancarpidine, Solasod-5-en-3β-ol, Solasod-5-en-3β-ol (7CI,8CI), Solasodin

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About This Item

Empirical Formula (Hill Notation):
C27H43NO2
CAS Number:
Molecular Weight:
413.64
EC Number:
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

assay

≥95% (HPLC)

form

powder

optical activity

[α]/D -88 to -98°, c = 0.2 in methanol

color

white to beige

solubility

DMSO: 0.5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

C[C@@H]1[C@]2(NC[C@H](C)CC2)O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC=C6C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]31[H]

InChI

1S/C27H43NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28-29H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1

InChI key

KWVISVAMQJWJSZ-VKROHFNGSA-N

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Application

Solasodine has been used in viability assays.

Biochem/physiol Actions

Solasodine is a neuroprotective antioxidant glycoalkaloid of Solanum species. Solasodine increases superoxide dismutase (SOD), catalase (CAT),and glutathione (GSH) levels, while reducing lipid peroxidation (LPO) and nitric oxide (NO) levels in the brains of ischemia/reperfusion (I/R)-injury model in rats. Also, Solasonine displayed multiple activities including, anti-cancer and leishmanicidal activities.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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