SML1720

ATI-2341 trifluoroacetate salt

≥95% (HPLC)

• Synonym(s): ATI 2341 trifluoroacetate salt, N-(1-Ohexadecyl)-L-methionylglycyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-lysyl-L-leucyl-L-arginyl-L-seryl-L-methionyl-L-threonyl-L-α-aspartyl-L-lysyl-L-tyrosyl-L-arginyl- L-leucine, Pal-MGYQKKLRSMTDKYRL, Pal-Met-Gly-Tyr-Gln-Lys-Lys-Leu-Arg-Ser-Met-Thr-Asp-Lys-Tyr-Arg-Leu
• Empirical Formula (Hill Notation): C₁₀₄H₁₇₈N₂₆O₂₅S₂ · xC₂HF₃O₂
• CAS Number: 1337878-62-2
• Molecular Weight: 2256.82 (free base basis)
• NACRES: NA.77
• UNSPSC Code: 12352200
• Assay: ≥95% (HPLC)
• Form: film

Properties

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: film
• color: colorless
• shipped in: wet ice
• storage temp.: −20°C

Description

Biochem/physiol Actions

ATI-2341 is a potent and selective allosteric agonist of chemokine CXC-type receptor 4 (CXCR4) that functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 does not promote β-arrestin recruitment. ATI-2341 promotes the mobilization of PMNs and HSPCs in the peripheral circulation of both mice and monkeys.

ATI-2341 is a potent and selective allosteric agonist of chemokine CXC-type receptor 4 (CXCR4).

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable